Eric Hwang Lab

Our lab is interested in studying the behavior of neurons, which allows the neuron to establish functional networks or adjust to certain developmental or environmental changes. For neurons to properly behave, they rely on the dynamic interaction of multiple cytoskeletal systems: microtubules, actin filaments (also known as microfilaments), and intermediate filaments. We are currently studying the behavior of neurons during normal or pathological conditions (such as nerve injury, neurodevelopmental disorders, and neurodegenerative disorders). Our lab uses various techniques, including cell biology, molecular biology, optogenetics, biochemistry, bioinformatics, biophysics, and material science. The image above is an aggregation of neurons derived from embryonic stem cells. This little ball possesses a brain-like structure and behavior. The actin cytoskeleton is shown in red, the neuron-specific microtubule in green, and DNA in blue. The video below demonstrates a regenerative behavior after axons sustained a surgical incision.

Our lab does not run on a hierarchical system. This means every student can discuss with the professor in person. This also means every student will be responsible for her/himself. In addition, new students do not need to worry about lacking background knowledge. If you are willing to learn, we will provide all the training and skills you need to succeed in the lab.

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我們的實驗室致力於研究神經元的行為，這使得神經元能夠建立功能性網絡或適應特定的發育或環境變化。要能產生適當的行為，神經元依賴於多種細胞骨架系統的交互作用，包括微管、微絲、中間絲。我們目前正在研究神經元在正常或病理條件（如神經損傷、神經發育障礙、神經退化性疾病）下的行為。實驗室採用多種技術，包括細胞生物學、分子生物學、光遺傳學、生物化學、生物資訊學、生物物理學以及材料科學。上圖顯示了由胚胎幹細胞衍生的神經元聚合體。這個小球體具有類似大腦的結構和行為。微絲以紅色顯示，微管以綠色顯示，DNA 以藍色顯示。而下面的影像展示了神經軸突經手術切斷後神經元的再生行為。

我們的實驗室不採用層級制度，這意味著每位學生都可以直接與教授討論，這也意味著每位學生都需要對自己負責。此外，新學生不必擔心缺乏背景知識。只要你肯學，我們將提供所有必要的訓練和技能以確保你在實驗室能順利取得成果。